Saturdays in. Must be 21+. Open 24 hours, 7 days a week! What's happening. . It's a warm, friendly environment with slot machines. A warm and friendly environment with slot machines at the Main Casino. Indulge. #1 Best Value of 24 Mexico Casino Hotels ; 2. Win. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Learn More. Colorful bingo cards and round bingo balls w/numbers. The Travel center includes a casino area with 45 slot machines. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. These casinos and gaming sites are owned by 14 New Mexico. Sky City Casino is open 24 hours daily. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. 1. The Pyramid Cancun · 4, reviews. at Isleta Resort & Casino. No Smoking Facility. Unwind. With three live entertainment venues, you'll find something around every corner. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. #2 Best Value of 24 Mexico. Excite. Swirls of Cash. Seadust Cancun Family Resort · 6, reviews. Our New Mexico casino is open 24/7 daily. Upcoming Events.