. Excite. Unwind. Learn More. 1. With three live entertainment venues, you'll find something around every corner. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Upcoming Events. Sky City Casino is open 24 hours daily. No Smoking Facility. Win. Must be 21+. Indulge. Open 24 hours, 7 days a week! What's happening. It's a warm, friendly environment with slot machines. Our New Mexico casino is open 24/7 daily. Colorful bingo cards and round bingo balls w/numbers. Swirls of Cash. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Saturdays in. A warm and friendly environment with slot machines at the Main Casino. #1 Best Value of 24 Mexico Casino Hotels ; 2. #2 Best Value of 24 Mexico. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. The Travel center includes a casino area with 45 slot machines. at Isleta Resort & Casino. These casinos and gaming sites are owned by 14 New Mexico. The Pyramid Cancun · 4, reviews. Seadust Cancun Family Resort · 6, reviews. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day.